This flaw could lead to the execution of attacker-supplied code via email, web or any other avenue in which Internet Explorer is used. This includes software which uses the web browser activex. All users of Internet Explorer are potentially affected because this is a Macromedia signed ocx. NT Bugtraq advises users to upgrade your Flash version immediately to version 6, revision 29, which does not contain the vulnerability.
eEye Digital Security (Advisory): Macromedia Flash Activex Buffer Overflow