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I bought a new Arduino Uno clone SMD that uses a CH340 chip. When I plug in the USB cable my Windows “operating system” could not detect the device, even though I installed ch340ser.exe.

Then I connected my Arduino Uno clone using a TTL USB to serial adaptor... Tx to Rx, Rx to Tx, 5 volt to VIN, and GND to GND.

I somehow managed to upload the Blink sketch to my Arduino Uno using that connection. But the success rate is low. I need to do it several times and press the reset button several times before it succeeds at uploading.

Is there any other pin that need to be connected to VCC or GND during upload process?

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I think you also need the DTR signal to RST to allow a reset signal to initiate the upload. You are doing that manually and will need to push the reset button at the right time (i.e. push reset and the quickly start upload). Also please check Vin. If I remember correctly that goes through a regulator and there will be a voltage drop (i.e. 5V will not be 5V on the board). arduino.cc/en/uploads/Main/arduino-uno-schematic.pdf – Mikael Patel Dec 17 '15 at 9:27

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